| Do., 29. Nov. 16:50 Uhr | ||||||
| Gr K | FK Astana | -:- | Dynamo Kiew | |||
| Gr G | Spartak Moskau | -:- | SK Rapid Wien | |||
| Do., 29. Nov. 18:55 Uhr | ||||||
| Gr L | BATE Borissow | -:- | Videoton FC | |||
| Gr A | Bayer Leverkusen | -:- | Ludogorez Rasgrad | |||
| Gr C | Girondins Bordeaux | -:- | SK Slavia Prag | |||
| Gr B | Red Bull Salzburg | -:- | RB Leipzig | |||
| Gr J | FK Krasnodar | -:- | Akhisarspor | |||
| Gr E | FK Qarabag | -:- | Sport. Lissabon | |||
| Gr D | Fenerbahce Istanbul | -:- | GNK Dinamo Zagreb | |||
| Gr F | AC Mailand | -:- | F91 Düdelingen | |||
| Gr D | RSC Anderlecht | -:- | Spartak Trnava | |||
| Gr F | Betis Sevilla | -:- | Olympiakos | |||
| Gr B | Rosenborg Trondheim | -:- | Celtic Glasgow | |||
| Gr E | Vorskla Poltava | -:- | FC Arsenal | |||
| Gr C | St. Petersburg | -:- | FC Køpenhagen | |||
| Gr A | FC Zürich | -:- | AEK Larnaka | |||
| Do., 29. Nov. 21:00 Uhr | ||||||
| Gr H | Apollon Limassol | -:- | Lazio Rom | |||
| Gr L | FC Chelsea | -:- | PAOK Saloniki | |||
| Gr H | Eintracht Frankfurt | -:- | Olympique Marseille | |||
| Gr K | FK Jablonec | -:- | FC Stade Rennes | |||
| Gr I | Malmö FF | -:- | KRC Genk | |||
| Gr G | Glasgow Rangers | -:- | FC Villarreal | |||
| Gr I | Sarpsborg 08 | -:- | Besiktas Istanbul | |||
| Gr J | Standard Lüttich | -:- | FC Sevilla | |||